Endocrine Abstracts

Introduction: Papillary thyroid carcinomas (PTC) represent up to 87% of all thyroid cancers with an incidence that has doubled over the past 30 years. Hashimoto’s thyroiditis (HT) and Graves’ disease are two autoimmune thyroid diseases representing the most common causes of hypothyroidism and hyperthyroidism, respectively. Although PTC with coexisting HT has been reported in literature, its association with GD is not a common condition. Herein, we report three cases ...

Introduction: Retrospective analysis has shown that approximately 17–84% of patients suffering from primary hyperparathyroidism have a concomitant thyroid disease. However, it still remains controversial whether these two pathologies happen coincidental or are caused by specific risk factors or genetic changes. In this study we aimed to evaluate concurrently detected thyroid pathologies in patients who underwent surgery for primary hyperparathyroidism.<p class="abstex...

Introduction: Ganglioneuromas (GN) are rare benign tumors arising from the neural crest tissue and are most commonly located in the posterior mediastinum and retroperitoneum; they are rarely found in the adrenal gland. We report a case of a female patient with adrenal ganglioneuroma.Observation: A 51-year-old female patient with no previous comorbidities was admitted to our hospital. She had no significant past medical or surgical history. She had sympto...

Introduction: Polycystic ovary syndrome (PCOS) is a heterogeneous disorder, characterized by chronic anovulation and hyperandrogenism. Hirsutism, defined as excessive terminal hair that appears in a male pattern in a woman, is frequently present in patients with PCOS. We aimed to determine the clinical and biological characteristics of hirsute patients with PCOS.Methods: It was a retrospective study included 30 women diagnosed with PCOS according to the ...

Introduction: The reactive pituitary gland enlargement is a non-neoplastic growth of at least one pituitary lineage, which can often be essential or secondary to prolonged deficit of a gland target. It may be difficult to differentiate from functional pituitary adenomas. Herein we report a case of pituitary hyperplasia secondary to congenital primary hypothyroidism diagnosed at the age of 38 years.Observation: A 38-year-old female patient presented with ...

Introduction: Myasthenia gravis is an autoimmune neuromuscular disease characterized by the presence of anti-acetylcholine receptor antibodies. It can be isolated or associated with other auto-immune conditions. Graves’ disease is an autoimmune disorder typically characterized by the presence of circulating autoantibodies that tie to and stimulate the thyroid hormone receptor. Coexisting myasthenia gravis and Graves’ disease is a rare but well recognized condition. T...

IntroductionThe insulin tolerance test (ITT) is the gold standard for the assessment of the integrity of the hyopothalamo-pituitray adrenal axis. it’s major drawbacks are the mandatory presence of an experienced physician and continuous supervision to detect any complication. Our study aims to evaluate the indications and the outcomes of the ITT performed in our department.Patients and methodsWe conducte...

IntroductionFahr’s syndrome (FS) is a rare neurodegenerative disorder. It’s characterized by abnormal calcifications in basal ganglia and cerebral cortex inducing neuropsychiatric disorders and cognitive impairment. The aim of our study was to assess the prevalence of FS, its characteristics, and its associated factors in patients with permanent hypoparathyroidism.MethodsWe conducted a cross-section...

IntroductionHomeostasis model assessment for insulin resistance (HOMA-IR) is widely used as a marker of insulin resistance. However, it reminds an expensive maker requiring insulin dosage. Several studies tried to found simple alternative predictors of insulin resistance such as triglycerides to HDL-C ratio with conflicting reported findings. The aim of our study was to investigate the usefulness of the atherogenic index of plasma (AIP) and the visceral ...

IntroductionNasopharyngeal carcinoma is characterized by distinct geographical distribution and is particularly prevalent in East and Southeast Asia. Environmental factors, genetic structure, and Epstein Barr virus infection are involved in the etiology of the disease. While nasal and otological symptoms are the most common (80%), intracranial extension is prevalent among 8% of cases and pituitary localization is rarely described in the literature. We re...